The centromere: a crucial point of vulnerability during cell division

Centromeres are specific regions on each chromosome essential for faithful cell division. A team at the Institut Curie and the CNRS led by Dr Daniele Fachinetti have just identified mechanisms involved in maintaining centromere stability that until now, have been little explored. Published in Molecular Cell on February 14, 2024, these results open numerous avenues of research into centromere instability that will have positive impacts in targeting certain pathologies such as cancer.